Biological properties of chimeric West Nile viruses
نویسندگان
چکیده
منابع مشابه
Differential Virulence and Pathogenesis of West Nile Viruses
West Nile virus (WNV) is a neurotropic flavivirus that cycles between mosquitoes and birds but that can also infect humans, horses, and other vertebrate animals. In most humans, WNV infection remains subclinical. However, 20%-40% of those infected may develop WNV disease, with symptoms ranging from fever to meningoencephalitis. A large variety of WNV strains have been described worldwide. Based...
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Until recently, West Nile (WN) and Kunjin (KUN) viruses were classified as distinct types in the Flavivirus genus. However, genetic and antigenic studies on isolates of these two viruses indicate that the relationship between them is more complex. To better define this relationship, we performed sequence analyses on 32 isolates of KUN virus and 28 isolates of WN virus from different geographic ...
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The biological properties of homogeneous populations of feline immunodeficiency viruses derived from infectious, molecular clones of the TM1, TM2 and Petaluma strains were compared. Differences in infectivity for Crandell feline kidney (CRFK) cells, and in syncytium formation and replication kinetics in a feline T lymphoblastoid cell line (MYA-1 cells) were observed. To investigate the basis of...
متن کاملWest Nile Virus Infection West Nile Fever, West Nile Neuroinvasive Disease, West Nile Disease, Near Eastern Equine Encephalitis, Lordige
West Nile virus (WNV) is an avian virus that can cause fatal disease in some species of mammals, reptiles and birds. Most clinical cases occur in humans and horses. Approximately 80% of infected humans remain asymptomatic; 20% have flulike symptoms. Less than 1% develop meningitis, encephalitis or acute paralysis, but some of these cases are fatal or result in permanent impairment. Neurological...
متن کاملBiological and phylogenetic characteristics of West African lineages of West Nile virus
The West Nile virus (WNV), isolated in 1937, is an arbovirus (arthropod-borne virus) that infects thousands of people each year. Despite its burden on global health, little is known about the virus' biological and evolutionary dynamics. As several lineages are endemic in West Africa, we obtained the complete polyprotein sequence from three isolates from the early 1990s, each representing a diff...
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ژورنال
عنوان ژورنال: Virology
سال: 2006
ISSN: 0042-6822
DOI: 10.1016/j.virol.2006.02.013